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The Week 6 NFL schedule will conclude on Monday Night Football when Tenne see hosts Buffalo. Caesars Sportsbook lists Buffalo as a 5.5-point road favorite in the latest Week 6 NFL odds. The Bills will have to avoid a letdown following their impre sive win at Kansas City last Sunday. Tenne see bounced back from a lo s to the with a 37-19 win at Jacksonville and now faces one of the larger spreads of the week.Is Monday Night Football one of the Week 6 NFL lines that you should avoid? Or will lead his team to a fifth straight win? Whether you're thinking of making Week 6 on these games or others, be sure to .The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 6 of the 2021 season on an incredible 125-83 run on top-rated NFL picks that dates back to the 2017 season Brandon Manning Men Jersey .The model also ranked in the top 10 on NFLPickWatch four of the past five years Bernie Parent Kids Jersey on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up. Now, it has turned its attention to the latest from Caesars and locked in picks for every NFL matchup. .Top Week 6 NFL predictionsOne of the model's strongest Week 6 NFL picks is that the (-3.5) cover the spread against the in well over 50 percent of simulations. The Raiders' injury-riddled secondary faces Broncos quarterback , who is throwing the ball deep more than he ever has while still maintaining the best completion rate and overall performance of his career.SportsLine's model projects a six-point Broncos win and has Denver covering the spread in well over 50 percent of simulations. That's the same mark the model gives the over, which cashes in well over 50 percent of simulations. The point total for the game is at 44, moving slightly after opening at 44.5. Another one of its Week 6 NFL predictions: The (-3) cover against the well over 50 percent of the time. Baltimore picked up its fourth consecutive victory when it erased a 22-3 deficit against Indianapolis on Monday. Quarterback completed 37-of-43 pa s attempts for a career-best 442 yards and four touchdowns. He has turned into one of the league's top pa sing quarterbacks through the first five weeks of the season.Los Angeles has struggled in its recent visits to the Eastern Time Zone, going 1-3 in its last four trips. The Chargers have allowed the most rushing yards of any team in the NFL, which does not bode well against an explosive Baltimore offense. Los Angeles allowed 230 rushing yards against Cleveland and is being gashed for 157.6 rushing yards per game.SportsLine's model is projecting Baltimore to run for nearly 150 yards, while Jackson is expected to throw for another 250. It will be difficult for Los Angeles to match those numbers, which is why the Ravens are covering this spread in well over 50 percent of simulations. How to make Week 6 NFL picksThe model has also made the call on who Chris Bigras Men Jersey wins and covers in every other game on the Week 6 , and it's calling for a Super Bowl contender to go down hard. .So what NFL picks can you make with confidence? And which Super Bowl contender goes down hard? Check out the latest NFL odds below, then , and find out.Week 6 NFL odds, spreads, linesSunday, Oct. 17 at (+3.5, 47) Featured Game | Jacksonville Jaguars vs. Miami Dolphins Moneyline Spread Total JAC MIA at (-10, 43) Featured Game | Indianapolis Colts vs. Houston Texans Moneyline Spread Total IND HOU at (+4.5, 44) Featured Game | Chicago Bears vs. Green Bay Packers James Van Riemsdyk Jersey Moneyline Spread Total CHI GB at Washington (+6.5, 55.5) Featured Game | Washington Commanders vs. Kansas City Chiefs Moneyline Spread Total WAS KC at (+1, 46) Featured Game | Carolina Panthers vs. Minnesota Vikings Moneyline Spread Total CAR MIN Chargers at Ravens (-3, 52) Featured Game | Baltimore Ravens vs. Los Angeles Chargers Moneyline Spread Total BAL LAC at (+3.5, 47.5) Featured Game | Detroit Lions vs. Cincinnati Bengals Moneyline Spread Total DET CIN at (+9.5, 48.5) Featured Game | New York Giants vs. Los Angeles Rams Moneyline Spread Total NYG LAR at (-3.5, 49.5) Featured Game | Cleveland Browns vs. Arizona Cardinals Moneyline Spread Total CLE ARI Raiders at Broncos (-3.5, 44) Featured Game | Denver Broncos vs. Las Vegas Raiders Moneyline Spread Total DEN LV at (+3.5, 51) Featured Game | New England Patriots vs. Dallas Cowboys Dale Weise Jersey Moneyline Spread Total NE DAL at (-5, 42.5) Featured Game | Pittsburgh Steelers vs. Seattle Seahawks Moneyline Spread Total PIT SEA Monday, Oct. 18 at (+5.5, 54) Featured Game | Tenne see Titans vs. Buffalo Bills Moneyline Spread Total TEN BUF